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One latest study from Yale University found that vanillin — an extract of the vanilla bean — transforms into chemical compounds known as acetals when aerosolized. Those chemical substances, the researchers stated, may be especially irritating to the lungs and cause damage when inhaled. Studies have proven that breathing in aerosolized propylene glycol could contribute to bronchial asthma. And a 2012 case report involved a lady who developed a condition called exogenous lipoid pneumonia after vaping for about six months.